The Chip Cooling Model and Route Optimization with Digital Microfluidics

Optical sensing for on-chip digital microfluidics

A digital microfluidic architecture is introduced for micron-scale localized fluid actuation and in in-situ optical sensing. Contemporary device integration challenges related to localization and device scalability are overcome through the introduction of a bi-layered digital microfluidic multiplexer. Trinary inputs are applied through differential combinations of voltage signals between upper ...

Digital microfluidics chip with integrated intra‐droplet magnetic bead manipulation

Electrowetting-on-dielectric (EWD) droplet actuation has been used widely in handling liquid in small quantities in many biological applications (Fair et al. 2007; Miller and Wheeler 2009; Boles et al. 2011; Welch et al. 2011). The droplet is manipulated by applying voltage to EWD electrodes buried beneath an insulator (Fair et al. 2007; Boles et al. 2011; Welch et al. 2011). Many droplet funct...

Portable High Throughput Digital Microfluidics and On-Chip Bacteria Cultures

Digital microfluidics: is a true lab-on-a-chip possible?

The suitability of electrowetting-on-dielectric (EWD) microfluidics for true lab-on-a-chip applications is discussed. The wide diversity in biomedical applications can be parsed into manageable components and assembled into architecture that requires the advantages of being programmable, reconfigurable, and reusable. This capability opens the possibility of handling all of the protocols that a ...

Digital microfluidics.

Digital microfluidics (DMF) is an emerging liquid-handling technology that enables individual control over droplets on an open array of electrodes. These picoliter- to microliter-sized droplets, each serving as an isolated vessel for chemical processes, can be made to move, merge, split, and dispense from reservoirs. Because of its unique advantages, including simple instrumentation, flexible d...